Developing therapeutics that target macrophages.
A Human Macrophage
A new category of medicine.
Our society's most valuable drugs for autoimmune disorders have been derived from stress signals that are emitted by the central nervous system— corticosteroids, epinephrine, thyroid hormone, and catecholamines are all potent immune suppressive drugs that have given physicians the ability to combat autoimmune diseases.
To further expand medicine for autoimmune disorders, Serenity is focusing on the communication network between the central nervous system and macrophages. Macrophages are a key type of immune cell that play significant roles in autoimmune diseases, and serves as a unique starting point to potentially address unmet needs for lupus, graft-versus-host-disease, and many other severe conditions.